New insulin capsules available for diabetic patients as these new insulin capsules could be game-changing for diabetic patients.
Sources has confirmed that Australian scientists have designed an oral capsule that can be used to provide required insulin in the body.
The new insulin capsules are absorbed in the small intestine as this drug contains a lipid-based nanomaterial to protect it from the low pH (high acidity) of the stomach.
Experimental studies on animals have shown the positive results capsule to be effective at delivering slow-acting insulin, with results that were 50% better than injection delivery.
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The scientists plan to improve the design and move on to human trials.
1. How does Oral Insulin Works?
Insulin is typically made of smaller pieces of proteins called peptides. Orally administered insulin has previously been prepared but the severe pH levels in the gastrointestinal tract degraded the peptides that caused the drug to lose its functionality. Other protein drugs run into the same difficulty.
To get around this problem, the scientists encapsulated the insulin in a lipid-based nanomaterial placed inside an enteric capsule. The enteric capsule’s polymeric coating protects against the low pH of the stomach.
“The capsule has a special coating designed to not break down in the low pH environment of the stomach, before the higher pH levels in the small intestine trigger the capsule to dissolve,” said Jamie Strachan, lead author of the study.
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“We package the insulin inside a fatty nanomaterial within the capsule that helps camouflage the insulin so that it can cross the intestinal walls.” he further added.
2. Precautions for Diabetic Patients
Following are five precautions that diabetic patients should take to manage their condition and reduce the risk of complications:
2.1 Maintain a Healthy Diet
Diabetic patients should consume a balanced diet rich in fiber, whole grains, fruits, and vegetables while limiting their intake of saturated fats, trans fats, and added sugars.
They should also avoid processed foods and sugary drinks, as these can cause blood sugar levels to spike.
2.2 Stay Physically Active
Exercise can help control blood sugar levels, improve circulation, and promote overall health.
Diabetic patients should aim to engage in at least 150 minutes of moderate-intensity aerobic exercise per week, as well as strength training exercises.
2.3 Monitor Blood Sugar levels Regularly
Diabetic patients should regularly check their blood sugar levels as directed by their healthcare provider.
This can help them adjust their diet, exercise, and medication as needed to keep their blood sugar levels in a healthy range.
2.4 Take Medications as Prescribed
Diabetic patients who require medication should take them as prescribed by their healthcare provider.
Skipping doses or adjusting medication without medical guidance can cause blood sugar levels to become too high or too low, leading to complications.
2.5 Attend Regular Check-ups
Diabetic patients should attend regular check-ups with their healthcare provider to monitor their blood sugar levels, manage their medications, and check for any complications.
Early detection and treatment of complications can help prevent further damage and improve outcomes.
